Crohn's Disease & IBD Psoriasis, Psoriatic Arthritis Connected To Crohn’S
With Crohn’s, as with psoriasis, the body mistakes healthy tissue for a foreign invader and attacks it. Crohn’s creates chronic inflammation of the intestinal wall at anywhere in the intestinal track, from the mouth to the rectum, which causes the wall to thicken.
Symptoms of Crohn’s include diarrhea, abdominal pain, cramping, bloody stools, reduced appetite and weight loss, and can be mild to severe. And, as with psoriasis, symptoms can come and go with periods of flares.
To conduct the study, Qureshi and his colleagues analyzed data from the Nurses’ Health Study (NHS) and NSH II, which had more than 174,000 participants. (The NHS is the world's largest, longest-running study of women's health.) The investigators identified women who had psoriasis when they enrolled and who reported developing inflammatory bowel disease in follow-up questionnaires. The investigators then confirmed the diagnoses with medical records and follow-up reports from both NHS studies.
The researchers identified approximately 4,400 women who had psoriasis at the start of their studies. During their follow-up, investigators found that 423 participants (about 10 percent) had developed Crohn’s disease (187) or ulcerative colitis (236), another type of inflammatory bowel disease.